. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. FMRFamide Mixed Responses 5HT FMRFamide 5hT. u|j|| I FIGURE 1. Examples of the responses of bivalve hearts to FMRFamide and 5HT. The species are identified from top to bottom and left to right. FMRFamide excitation: Geukensia demissa granosissima, 1 X 10~7 M; Dinocardium robustum, 3 X 10~7 M; Modiolus squamosus, 1 X 10~7 M. 5HT excitation: Mytella guvanensis, 3 X 10~7 M; Lampsilis ovata ventricosa, 1 X 10~6 M; Mytilus edulis, 1 X 10 6 M. FMRFamide inhibition: Elliptic icterina, 1 X 10~7 M; Lampsilis ovata ventricosa, 1 X 10~


. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. FMRFamide Mixed Responses 5HT FMRFamide 5hT. u|j|| I FIGURE 1. Examples of the responses of bivalve hearts to FMRFamide and 5HT. The species are identified from top to bottom and left to right. FMRFamide excitation: Geukensia demissa granosissima, 1 X 10~7 M; Dinocardium robustum, 3 X 10~7 M; Modiolus squamosus, 1 X 10~7 M. 5HT excitation: Mytella guvanensis, 3 X 10~7 M; Lampsilis ovata ventricosa, 1 X 10~6 M; Mytilus edulis, 1 X 10 6 M. FMRFamide inhibition: Elliptic icterina, 1 X 10~7 M; Lampsilis ovata ventricosa, 1 X 10~8 M; Cyr- topleura costata, 1 X 10~7 M. 5HT inhibition: Geukensia demissa granosissima, 1 X 10~8 M; Lampsilis ovata ventricosa, 1 X 1CT5 M; Rangia cuneata, 1 X 10~6 M. FMRFamide mixed responses: Rangia cuneata, 1 X 10~7 M; Pseudochama exogyra, 1 X 10~6 M; Corbicula manilensis, 3 X 10"I0 A/; Noetia ponderosa, 1 X 10"5 A/; 5HT mixed responses: Villosa lienosa, 1 X 10~5 A/; Lampsilis claibornensis, 1 X 10~6 M; Corbicula manilensis, 3 X 10~9 A/; Anadara tuberculosa, 3 X 10~7 A/. Drugs were added to the bath at the arrows. Time: 1 min. Tables and plots Tabulating the effects. The individual responses making up each DRP were examined for excitatory and inhibitory component effects, and the threshold for each effect was determined. Thresholds, rather than ED50s, were recorded because the effects changed qualitatively with dose in many preparations. The data were compiled by species and are presented in Table I. The percentage of responding preparations affected in each of the two modes and the number of preparations failing to respond in either mode are indicated for each species. Unresponsive hearts were challenged with very high doses of agonist (1-3 X 10~5 M) and these responses (or lack of them) are also recorded in Table I. Table I thus provides the initial characterization of the species responses to FMRFamide and 5HT. Subsequent derivations are intended to illustrate


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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology