. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). me in-stances o])isthotoiios occurred. The lumbar region was 1. : Miinchen. nied. Wchnsflir., .a. 4, lOOS. ;-j;i; Neurol. CentniMjl., .Tan. ](;. UHi!i. p. ?-. Van Lier: IScitriise zui l<lin. liii, 41.!.;,. Wossidlo: Aleli. t. klin. UlliN, Lwxvi. HUT. exaniineil iers tindinus were similar. They used rabhits. Wos-sidlo concluded that tropacocain was less dangerous thanstovain or novocain and that changes occurred in thecells in lumbar anesthesia, hut t


. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). me in-stances o])isthotoiios occurred. The lumbar region was 1. : Miinchen. nied. Wchnsflir., .a. 4, lOOS. ;-j;i; Neurol. CentniMjl., .Tan. ](;. UHi!i. p. ?-. Van Lier: IScitriise zui l<lin. liii, 41.!.;,. Wossidlo: Aleli. t. klin. UlliN, Lwxvi. HUT. exaniineil iers tindinus were similar. They used rabhits. Wos-sidlo concluded that tropacocain was less dangerous thanstovain or novocain and that changes occurred in thecells in lumbar anesthesia, hut that they were not seriousenough to prcvciit the use of drugs in tliis 5.—Sectiou llUuiiKli tlif lumbar riSjiim i frum ) showing intonse diwneration of the columus. IJchn could not demonstrate any changes in the cellsof the anterior horns until after three days; then theywere found in the lumhar. thoiacic and cervical regions,and yet onlv a few cells in any one section were alteration began at the periphery of the cell, andthe nucleus becam^e perijjheral. Animals that had livedten to twonty-one days showed by the ^Marchi method,degeneration in the entire peri])hery of the cord and inthe entire posterior coluiims. in the latter apparentlysvstemic in character. Only cells in the anterior horns were affected; sensory cells were intact. Rehns report*is of findings obtained by Klose and ^og?t. The technie of our experiments consisted in jserform-ing lumbar puncture on five dogs with careful avoidanceof infection. The stovain solution used on Dogs D and]i was boiled. The dose of each stovain injection varied


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