. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). alum-acid fuchsin showed an extremelyvascular tissue made up of cells with round and oval nuclei, andmany neuroglia fibers. No nerve fibers are observed in any partof the section. AXIS-CYLINDERS IN CASES OF GLIOMA CEREBRI i37 Wcigert Section.—The cellular and vascular characters canstill be recognized, and a few swollen, beaded, medullary frag-ments can be seen (Fig. i). In the center of the section, wherethe nerve fibers seem to be least numerous, twenty-seven frag-ments were counted. Oc. i. Obj.


. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). alum-acid fuchsin showed an extremelyvascular tissue made up of cells with round and oval nuclei, andmany neuroglia fibers. No nerve fibers are observed in any partof the section. AXIS-CYLINDERS IN CASES OF GLIOMA CEREBRI i37 Wcigert Section.—The cellular and vascular characters canstill be recognized, and a few swollen, beaded, medullary frag-ments can be seen (Fig. i). In the center of the section, wherethe nerve fibers seem to be least numerous, twenty-seven frag-ments were counted. Oc. i. Obj. %. Whereas, if the % focused on the same area no medullary fragment could beseen. At the periphery of the section numerous medullary fibersare observed with each magnification. Bielschozvsky Section.—The character of the tissue can stillbe discerned and many axis-cylinders are seen in all parts of thesection (Fig. 2). In that portion of the section which showedthe least number of fibers, sixty-eight were counted with the% obj., and in the same field twenty-four were counted with. Fig. I. Weigert preparation from substance of tumor. Case I, show-ing a few medullated fragments. Oc. i, Ob. §. Fig. 2. Bielschowsky preparation from same block of tissue as showing many axis-cylinders. Oc. I, Ob. i. the Ye obj. The axis-cylinders had no definite direction, variedconsiderably in size, and showed decided evidences of degenera-tion in certain areas. The Internal Capsule.—The anterior third appears to be nor-mal by each of the three stains. The middle and posterior thirdsshow degenerative changes by all three methods, and a smallcapillary hemorrhage is observed in the posterior third, and someproliferation of the neuroglia cells. In the degenerated areas agreat many more axis-cylinders are observed in the silver prepa-ration than in either of the other two stains. The hemorrhagicarea shows a complete absence of medullated fibers in the CHARLES METCALFE BVRXES Weige


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