Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . carcinoma. The foDiis of degeneration occasionally seen in hard cancers are , mucoid, and hyaline, and, rarely, caseous necrosis. Melanoticor pigmentary, and calcareous infiltrations o-Mr Th<* mo<;t n^mnrk-able feature of some of these cases is theof the neoplasm; nodules that have developc . carcinoma) may cease to grow or even atrophy. There is evidence to See Ellis. Publications from the Laboratories of • I- lege Hospital, 1904, vol. i, reprint from Annals of Sii
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . carcinoma. The foDiis of degeneration occasionally seen in hard cancers are , mucoid, and hyaline, and, rarely, caseous necrosis. Melanoticor pigmentary, and calcareous infiltrations o-Mr Th<* mo<;t n^mnrk-able feature of some of these cases is theof the neoplasm; nodules that have developc . carcinoma) may cease to grow or even atrophy. There is evidence to See Ellis. Publications from the Laboratories of • I- lege Hospital, 1904, vol. i, reprint from Annals of Sii;graphy. 334 GENERAL PATHOLOGY. show that even visceral metastases may manifest retrogressive illustrating this peculiar phenomenon are exceedingly rarebut of undoubted occurrence.^ It is not known exactly what histo-logic alterations accompany the disappearance, but probably the changesare similar to those seen in the atrophic scirrhus. Scirrhous carcinoma is most frequent in the breast, uterus, stomach(pylorus), esophagus, rectum, and kidney; it is rare in ovary, testes,and Fig. 17S.—Glandular Carcinoma of the Liver (Scirrhus).Tissue fi-xed in corrosive sublimate, infiltrated with paraffin, stained with and eosin, and mountedin balsam. Dra\\Ti from i-inch A-inch oc. A, A, A, A, A. Connective-tissue stroma. B, B, B, B, cells occupying, but not filling, the alveoli. Communication between the alveoli is well shown, aspractically all the large alveoli communicate. Just below C is shown a small alveolus containing two epithelialcells, and a little to the right is a similar alveolus. A number of efforts were made to demonstrate that theclear space surrounding the epithelial cells was occupied by some material that would not stain by the methodused in the section from which this drawing was made. All efforts to secure such demonstration were is probable that the space is produced by the contraction of the epi
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