American journal of pharmacy . ring the cool, moist nights in the latter part of August,and in the months of September and October. The following table gives the mean temperature and rainfall 622 Belladonna Cultivation. i Am. Jour. Pharm.( September, 1920. for this locality during the growing months for the last four climate is not an ideal one for the growing of this plant. Precipitation. Inches. Mean Temperature. 1916. 1917. 1918. 1919. 1916. 191 7. 1918. 1919. 3-52 3- II 48 4 3-17 5-11 511 53 9 60 . 7 3-39 5-31


American journal of pharmacy . ring the cool, moist nights in the latter part of August,and in the months of September and October. The following table gives the mean temperature and rainfall 622 Belladonna Cultivation. i Am. Jour. Pharm.( September, 1920. for this locality during the growing months for the last four climate is not an ideal one for the growing of this plant. Precipitation. Inches. Mean Temperature. 1916. 1917. 1918. 1919. 1916. 191 7. 1918. 1919. 3-52 3- II 48 4 3-17 5-11 511 53 9 60 . 7 3-39 5-31 69 0 67 .0 70. 2 4-54 74 0 73-2 73-6 73-6 74 2 750 3 63 3-32 2 .01 61 4 62 .7 Oct 7-34 3-13 55-5 51 4 57-4 In localities where the frost penetrates deeply into the ground,roots must be taken up in the Fall and protected against freezing,and in turn re-planted in the open ground in the Spring. This isthe method which we Portion of field of first-year belladonna plants. Inset shows anenlarged branch in fruit and flower. The plant seems to thrive best in deep, well drained, moist loam,with an abundance of lime. After many attempts at soil fertiliza-tion, it was found that stable manure was the best fertilizer. Variousforms of fertilizer mixtures, such as are used in drug gardens, willincrease the growth of the plant, but apparently will have but littleeffect upon the alkaloidal content. Am. Jour. Pharm. )September, 1920. | Belladonna Cultivation. 623 Cultivation.—So far as we are aware, no successful cultiva-tions have been made on this Continent by sowing the seed in theopen ground. Seeds of belladonna germinate very slowly. Aftervarious attempts to hasten germination by the application of chem-ical and mechanical measures, we found the most satisfactorymethod was to sow the seed in the cold-frame in December, and al-low them to lie dormant until February. About this tim


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