AMAarchives of neurology & psychiatry . vessels were dilated, and there were manvnew formed capillaries. Some vessels were surrounded by a ring ofsyncytial cytoplasmic glial cells (Fig. 8). Masses of pigment granuleswere contained within the proliferated adventitial and endothelial nerve fibers in places appeared swollen and spindle-shaped but notfragmented. In short, there was a generalized condition of toxicencephalitis. 166 AKCHIIES or StLLROLOCV AS I) ISYC II LIT RV ( )f the torei^foing changes those most constant were: general toxicencephalitis, the colloid masses and the ])roce
AMAarchives of neurology & psychiatry . vessels were dilated, and there were manvnew formed capillaries. Some vessels were surrounded by a ring ofsyncytial cytoplasmic glial cells (Fig. 8). Masses of pigment granuleswere contained within the proliferated adventitial and endothelial nerve fibers in places appeared swollen and spindle-shaped but notfragmented. In short, there was a generalized condition of toxicencephalitis. 166 AKCHIIES or StLLROLOCV AS I) ISYC II LIT RV ( )f the torei^foing changes those most constant were: general toxicencephalitis, the colloid masses and the ])rocesses in the transition most of the cases the demarcation zone, as stated, was absent, andinvasion of the ganglions by cancer cells was not observed. In thesecases the tumor masses often presented large areas of central necrosis(Fig. 9) in which no cells could be detected. Surrouiifling such areasthere were scattered, shrunken and poorly stained carcinoma cells(intermediate zonej and next to these again a larger zone of more or. Fig. 10.—Pia-arachnoid—distended, the subarachnoid space packed with, cellbodies. A,A,A, foci of carcinoma separated from the proliferated pia (C,C)b\- an empty space which should be compared with the well formed pial cover-ing of the brain at —hyperplastic arachnoid. \an Ciieson ; X 60. less well jjreserved cancer tisstie. richlv >upplied with blood the most part blood vessels were lacking in the central and inter-mediate zones; if present, thev were dilated and enormouslv infiltratedwith well formed cancer cells. Such infiltrated vessels stood out asbeatitifullv stained islands in a colorless, necrotic mass (Fig. 9). The Pia-Arachuoid and Choroid Plexus.—Whatever the type andextent of parenchymatous destruction, changes were constantly present HASSIX-SfXGER—CEREBRAL CARCL\0.\LA 16; in the pia-arachnoid and the choroid plexus. The pial changes weremost marked when the tumor almost reached the membrane. The pia-arach
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Keywords: ., bookcentury1900, bookdecade1910, bookpublisherchica, bookyear1919
