. Annals of medical history. had this disease in Pennsylvania,—these are not mentioned by Dr. Mitchell. 2. A very great anxiety with sickness andpain of the stomach attended with an excessiveconvulsive vomiting, which no medicine wouldscarce relieve. This appeared on the first orsecond daj, but more commonly on the thirdwhen it was generally fatal, by bringing onhiccough, inflammation of the stomach andviscera, with a large discharge by vomit, of ablack atrabilious matter like coffee grounds,mixed up with a bloody lymph, or coagulatedblood; which frequently put a period to thepatients life, th
. Annals of medical history. had this disease in Pennsylvania,—these are not mentioned by Dr. Mitchell. 2. A very great anxiety with sickness andpain of the stomach attended with an excessiveconvulsive vomiting, which no medicine wouldscarce relieve. This appeared on the first orsecond daj, but more commonly on the thirdwhen it was generally fatal, by bringing onhiccough, inflammation of the stomach andviscera, with a large discharge by vomit, of ablack atrabilious matter like coffee grounds,mixed up with a bloody lymph, or coagulatedblood; which frequently put a period to thepatients life, tho some recovered under this 394 Annals of Medical History symptom, by an early discharge of this biaclcmatter by stool. 3. The atrabilious humour, as Dr. Mitchellcalls it, was highly acrid, yet not so viscid asthat in Virginia, which gave it a more easypassage through the Bihary ducts, and beingthereby more easily pumped up by the convul-sive Reachings of the stomach, hence by itsgreater acrimony, it rendered this symptom. more violent and fatal, than It seems to havebeen in Virginia. This conclusion is rather interesting in viewof our present conception of the pathologyof ycHow fever and the pathologic physi-ology of its accompanying signs andsymptoms. In 1750 Dr. Adam Thompson publisheda paper On the Preparation of the Bodyfor the Small Pox. In this article, followingthe teaching of Boerhaave, Thompson urgedthe liberal use of mercury and antimony as apreparative measure. Whereupon Kearsleyprepared a brochure cMtitlcd A Letter to aIriend; Containing Remarks on a DiscourseProposing a l-*riparation of the Body for the Small Pox; and the Manner of Receivingthe Infection, which was published byB. Franklin and D. Hall in 1751. Introduc-ing the subject, Kearsley criticizes theunnamed author (Dr. Thompson) for hislack of familiarity with the W ritings of thelearned and experienced Physicians, xxx(whose) Rules of Practice in a Science,he caustically adds, (may) not be prosti-tuted t
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