. The breast: its anomalies, its diseases, and their treatment . coarse collagen and fibroglia, but considerable elastica may develop in it. That suchtissue is not preexistent in the part affected and brought into view through crowding and 48o THE BREAST compression, is shown by a study of cancer growths in the lymph nodes and liver wherevery little connective tissue is normally present but where great quantities appear in mostcases of cancerous invasion. There seems to be no uniformity in the proportion ofnewly formed connective tissue to epithelial tissue; in some cases there is comparativel
. The breast: its anomalies, its diseases, and their treatment . coarse collagen and fibroglia, but considerable elastica may develop in it. That suchtissue is not preexistent in the part affected and brought into view through crowding and 48o THE BREAST compression, is shown by a study of cancer growths in the lymph nodes and liver wherevery little connective tissue is normally present but where great quantities appear in mostcases of cancerous invasion. There seems to be no uniformity in the proportion ofnewly formed connective tissue to epithelial tissue; in some cases there is comparativelylittle, in other cases much. The quantity formed, however, has much to do with the general character of thecancer itself. If the cancer grow without much proliferative change in the connectivetissue, there is apt to be a great preponderance of epithelial cellular tissue so that thetumor may be large and soft; when the connective-tissue reaction is marked and much newfibrillar tissue with a cicatricial quality develops, the cancer is apt to be small and Fig. 175.—Non-carcinomatous portion of a carcinomatous breast showing dilated ducts. Thus arises the two chief clinical types—the encephaloid or soft and the scirrhus or hardcancers. As the primary cancer grows and its outlying cellular extensions invade the tissue,the normal parenchyma of the breast shows marked disturbance. Every breast that isthe seat of cancer shows marked changes of the kind described as abnormal interpret these changes to mean that the presence of the cancer effects stimula-tion of the mammary parenchyma, not that the mammary parenchyma, being primarilydisturbed, evolves the cancer. In proof of this it may be pointed out that cancer is notalone in effecting these abnormal involutional changes. They occur just as regularly insquamous-cell carcinoma, in tuberculosis, actinomycosis and other forms of localizeddisturbances, as in cancer. Further examination of cancerous breasts shows t
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbreast, bookyear1917
