. The elements of pathological histology with special reference to practical methods . ssue increase, but a granula-tion tissue develops on the wall of the alveoli, also owing to growthof the fixed cells and blood-vessels, and this permeates the plugsof exudation, gradually fills up the lumen of the alveoli, and then,together with the perivascular and peribronchial infiltrations, changesby the formation of fibroblasts into a connective tissue which becomescontinually firmer and is for the most part pigmented {cirrliosis).The new connective tissue in the alveoli is frequently developedonly from


. The elements of pathological histology with special reference to practical methods . ssue increase, but a granula-tion tissue develops on the wall of the alveoli, also owing to growthof the fixed cells and blood-vessels, and this permeates the plugsof exudation, gradually fills up the lumen of the alveoli, and then,together with the perivascular and peribronchial infiltrations, changesby the formation of fibroblasts into a connective tissue which becomescontinually firmer and is for the most part pigmented {cirrliosis).The new connective tissue in the alveoli is frequently developedonly from a portion of the alveolar wall, and then pushes itselfmore and more into the alveolus {b) in the form of a polypoid pro-tuberance. Owing to shrinkage of the connective tissue developedaround the bronchi, with simultaneous adhesion of the lung, bron-chiectases may result. The same effect may also be produced should INDURATION 279 the connective-tissue hyperplasia which occurs during the healing ofa pleurisy extend to the interlobular and peribronchial connectivetissue of the Pig. 139.—Commencing Induration of the Lung in Pneumonia of twenty daysSTANDING. X 285. (Alum cochineal.) a, Newly formed connective tissue; />, Alveoliinto which the newly formed connective tissue is growing in polypoid form ; r, Exuda-tion in the alveoli consisting of leucocytes, desquamated ei)ithclial cells, and serum;d. Alveolar septa infiltrated with small cells. The Diplococcus pneumonim is found in greatest abundance in thoseparts of the lung in which the disease is still most recent, andhence especially in the oedematous portions bordering on the area ofhepatisation, where it also frequently shows an easily-stained capsule(Fig. 138, d); whereas in the actual area of hepatisation, especiallythe grey, it may be completely or for the most part dead. It isfurthermore found in the exudation of those processes which are aptto complicate pneumonia, such as pleurisy, pericarditis, endocarditis


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895