Report of first expedition to South America, 1913 . esand also in fine granules. (Plate xv.) It is yellowishor yellowish-brown in color, and is present in both theendothelial leukocytes and also free in masses between thesplenic cells. The pigment is not black, and does notresemble black malarial pigment. It resembles melanin inthat it does not give the iron reaction. Whether in Oroyafever the anaemia partially results from the destruction of thered blood-cells through the circulation of hematin, as W. ^ believes to be the case in malaria, at the present timeis not clear. Bartonella ba


Report of first expedition to South America, 1913 . esand also in fine granules. (Plate xv.) It is yellowishor yellowish-brown in color, and is present in both theendothelial leukocytes and also free in masses between thesplenic cells. The pigment is not black, and does notresemble black malarial pigment. It resembles melanin inthat it does not give the iron reaction. Whether in Oroyafever the anaemia partially results from the destruction of thered blood-cells through the circulation of hematin, as W. ^ believes to be the case in malaria, at the present timeis not clear. Bartonella bacilliformis evidently produces. nopigmentation in its development in the red cells in the periph-eral circulation. No malarial parasites are visible in thesplenic sections in uncomplicated cases. The spleen is rich 1 Brown: J. Exper. Med., 1913, xviii, 96. ,^9.®. **^ © *• ^ P<./- :^><-v.:/=v^^ ft . %9^ ?- ® ^o Fig. 1Showing necrosis and the character of ^t:^ Fig. 2 Showing endothelial phagocytes in sinusoids, enclosing erythrocytes, erythroblasts, polymorphonuclear leukocytes, and pigment. Plate XIV — Oroya Fever Liver


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