Cholestasis, light micrograph


Light micrograph of cholestasis of a human liver. Cholestasis is a condition where bile cannot flow from the liver to the duodenum, due to either an obstruction in the bile duct system, or metabolic causes (frequently drug-induced). Pruritus (itching) and jaundice are frequent symptoms. There are brown granules in the hepatocyte (liver cell) cytoplasm, near the nucleus. The Kupffer cells have phagocytosed large amounts of bile.


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Photo credit: © JOSE CALVO / SCIENCE PHOTO LIBRARY / Alamy / Afripics
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Keywords: -, abnormal, bile, biliary, cholestasis, disease, disorder, healthcare, hepatic, hepatocyte, histological, histology, histopathological, histopathology, jaundice, light, liver, medical, medicine, micrograph, microscopy, pathology, pigment, tissue, unhealthy