. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 60 r. FIELDS NEAR SMALL WOUNDS 100 r 181 0 1 2 DISTANCE FROM THE WOUND (mm) Figure 1. Lateral wound potential in normal newt skin. A wound ca. mm in diameter was made in the middle hindlimb digit tip, and the transepithehal potential of the skin was measured at 0, 1. and 2 mm from the edge of the wound. The slope of the potential difference between the edge of the wound and a point mm away from the wound is taken as the lateral wound potential. In this case, the lateral wound potential was 66 mV/
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 60 r. FIELDS NEAR SMALL WOUNDS 100 r 181 0 1 2 DISTANCE FROM THE WOUND (mm) Figure 1. Lateral wound potential in normal newt skin. A wound ca. mm in diameter was made in the middle hindlimb digit tip, and the transepithehal potential of the skin was measured at 0, 1. and 2 mm from the edge of the wound. The slope of the potential difference between the edge of the wound and a point mm away from the wound is taken as the lateral wound potential. In this case, the lateral wound potential was 66 mV/mm. mm of the wounded digit tip one-half hour after wound- ing mV/mm ± mV/mm (range, 10 mV/mm to 88 mV/mm; n = 10). The comparable value for the stump fields was ca. 48 mV/mm (calculated from Mc- Ginnis and Vanable, 1986b). As wound healing oc- curred, more and more of the lateral potential drop oc- curred across the wound epithelium, rather than along the distal-most skin proximal to the wound (Fig. 2), as was the case with the healing of the limb amputation wounds studied by McGinnis and Vanable (1986b). When sodium channels were blocked with 30 nAI ben- zamil in APW containing mM CaCl2, the overall TEP diminished drastically, and usually reversed, so that the subintegumentary region was negative with respect to the outside (Fig. 3). A series of 8 measurements yielded a value mV ± mV (range, mV to + mV) for the TEP of the digit skin before wounding. One- half hour after wounding, the lateral potential in the first mm from the edge of the wound averaged mV/mm ± mV/mm (that is, in contrast to the nor- mal situation, the region close to the wound's edge was more positive than regions away from the edge), with a range mV/mm to mV/mm. Discussion If the cells that migrate to heal wounds in newt skin are as sensitive to electrical fields as typically are cells in. Please note that these images are extracted from sca
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
