The pathology and surgical treatment of tumors . t surface, as in cases of papilloma. SARCOMA. 533 The spindle-cells with a scanty intercellular substance constitute thewalls of the new capillary blood-vessels, as was first shown byWaldeyer. In all capillary vessels the endothelial cells are a new sarcomatous growth the vessels increase in size and are laterpushed apart by the cellular elements. The walls are thin and remainthin, so that finally the lumina of the vessels appear to be surroundedby only a single layer of endothelial cells (Fig. 379, c). The circula-tion in the capil
The pathology and surgical treatment of tumors . t surface, as in cases of papilloma. SARCOMA. 533 The spindle-cells with a scanty intercellular substance constitute thewalls of the new capillary blood-vessels, as was first shown byWaldeyer. In all capillary vessels the endothelial cells are a new sarcomatous growth the vessels increase in size and are laterpushed apart by the cellular elements. The walls are thin and remainthin, so that finally the lumina of the vessels appear to be surroundedby only a single layer of endothelial cells (Fig. 379, c). The circula-tion in the capillaries is active and the blood-pressure is considerable,and, as the walls are weak, the blood-pressure is communicated to thetissues of the tumor, in which event the tumor pulsates. In all histological varieties of sarcoma the cells are characterizedby the existence of a large nucleus, which in young tumors almostobscures the cell-protoplasm. In the spindle-cells the nucleus iscentrally located (Fig. 380). The giant-cells are multinuclear ( Fig. 380.—Spindle-cells from sarcoma (after Liicke). 381). The cells vary greatly in size and shape, but a certain uniformityis observed in each tumor. The shape of the cell is not only greatlyinfluenced by the structure of the mesoblastic tissue in which the tumororiginates, but also by the cell-environments. The cells are oftenmoulded into different shapes by pressure. The shape of the nucleusis determined by the shape of the cell. The nucleus is always clear,well-defined, and surrounded by a proper nuclear membrane. The con-tents of the nucleus vary according to the age of the cell. In youngand rapid-growing sarcoma the contents are rich in chromatin; laterthe chromatin is diminished and there appears a beautiful network ofchromatin threads that do not readily absorb staining material. One ortwo nucleoli which are deeply stained are always present. In young 534 PATHOLOGY AND TREATMENT OF TUMORS.
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
