. The American journal of anatomy. nctly separated from neighbor-ing groups, rendering the study of such a grou]3 in serial sections possi-])le and easy. This anatomical condition made it very easy, as will beshown, to trace the relation of an island to its acinus. In this earlystage it was not possible to find any arrangement of cells suggestive ofthe formative stages of the islands, nor was it possible to find the pecu-liar cells with rich eosinophilic protoplasm which Laguesse and Eenautcompare to the parietal or oxyntic cells of the gastric tubules, and whichthey consider to be the earlies
. The American journal of anatomy. nctly separated from neighbor-ing groups, rendering the study of such a grou]3 in serial sections possi-])le and easy. This anatomical condition made it very easy, as will beshown, to trace the relation of an island to its acinus. In this earlystage it was not possible to find any arrangement of cells suggestive ofthe formative stages of the islands, nor was it possible to find the pecu-liar cells with rich eosinophilic protoplasm which Laguesse and Eenautcompare to the parietal or oxyntic cells of the gastric tubules, and whichthey consider to be the earliest differentiation of cells destined to formislands. In the next preparation (Xo. 3), from an embryo 54 mm. in length,the early development of the islands can be easily seen. The freshness 28 53 54 11 73 60 78 (( 70 u 84 70 11 84 80 It 89 90 94 94 97 no measurement. supp( 3sed 3 months, length I mm., prob able 115 d ays. 116127130145160160170200205210 (1 11 11 11i( u 11 u 116127180145160160170200205210 Eichard Mills Pearce 449. JV. ai-^_ ^-i .*^ and excellent preservation of this specimen adapted it for a most carefuland accurate study of the relations and differentiation of the cells. Theglands are still represented by branching processes of cells, lying in anabundant stroma, but here and there a few processes which have becometubular are seen. The cells are closely crowded together, especially atthe periphery or growing portion of the process. They have ratherdeeply staining, round or oval vesicular nuclei, and a very small amountof slightly granular protoplasm. The protoplasm is readily demon-strable in those cells formingtubular processes; the nuclei areseen at the periphery, while theclear protoplasm at the attach-ment of the cells to the base-ment membranes forms a ringabout the lumen. Here andthere, and generally at the per-iphery, in either the solid or tu-bular processes, is occasionallyseen a much larger cell withdeeply staining chromatin andeither with clear or e
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Keywords: ., bookcentury1900, bookdecade1900, booksubjectanatomy, bookyear1901
