. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. REGENERATION AS MASS AND TIME 231 in a concentration range which yielded a 61 per cent decrease in the 1/t factor the length was affected only to the extent of six per cent. The use of higher concentrations however led quickly to drastic reductions in the amount of tissue transformed. In the case of azide in the range from 1 X 10~6 molar to 2 X 10~3 molar, the differential effect on the factors of the rate was not as clear-cut as in the case of cyanide. There was again however a tendency for the length to be less sensitive t
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. REGENERATION AS MASS AND TIME 231 in a concentration range which yielded a 61 per cent decrease in the 1/t factor the length was affected only to the extent of six per cent. The use of higher concentrations however led quickly to drastic reductions in the amount of tissue transformed. In the case of azide in the range from 1 X 10~6 molar to 2 X 10~3 molar, the differential effect on the factors of the rate was not as clear-cut as in the case of cyanide. There was again however a tendency for the length to be less sensitive to lower concentrations than \/t. Thus in experiment 10, 7 X 10~4 molar azide decreased 1/t by 43 per cent and length by eight per cent. In experiment 12, the same concentration resulted in a 38 per cent decrease in 1/t and a 12 per cent decrease in length. 20 00 ,3 3 CHLORETONE. ln(OI06) FIGURE 2. The effect of chloretone on rate (\/f) of regeneration (open circles), and on length of the regenerating primordium (half-closed circles). Data from experiment 6, Table I. Both cyanide and azicle presumably act by poisoning the cytochrome-cyto- chrome oxidase system. A study of their effects on both respiration and recon- stitution (Moog and Spiegelman, 1942) has however indicated that they follow different pathways in depressing the regeneration process, for cyanide inhibition of reconstitution was always accompanied by a strong depression of the respira- tory rate, whereas azide, in a concentration which invariably cuts the reconstitu- tion rate by at least 80 per cent, scarcely altered the rate of oxygen uptake at all. The data presented in Table II further indicate that the ultimate effect of azide differs from that of cyanide. In the case of cyanide a 20 per cent decrease in length is accompanied by a 70 per cent increase in time to constriction, but a. Please note that these images are extracted from scanned page images that may have been digitally enhanced f
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
