. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. 200 BIOLOGY OF THE LABORATORY MOUSE Osteoma.—This growth originates from bone and is a benign encapsu- lated tumor. It is composed mostly of dense compact bone, usually with little marrow (Fig. no). This is another uncommon form of tumor and is probably overlooked when small and inconspicuous. Lipoma.—This is a benign tumor of fat or adipose tissue and is usually composed of large fat cells. The tissue looks nearly normal but lacks. Fig. io8.—Epidermoid carcinoma of the skin. A, inguinal lymph node


. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. 200 BIOLOGY OF THE LABORATORY MOUSE Osteoma.—This growth originates from bone and is a benign encapsu- lated tumor. It is composed mostly of dense compact bone, usually with little marrow (Fig. no). This is another uncommon form of tumor and is probably overlooked when small and inconspicuous. Lipoma.—This is a benign tumor of fat or adipose tissue and is usually composed of large fat cells. The tissue looks nearly normal but lacks. Fig. io8.—Epidermoid carcinoma of the skin. A, inguinal lymph node metastasis of the carcinoma shown in Fig. io6 (X200); B. cellular detail of the tumor in Fig. 107 (X400). trabeculae, normal vascularity, and the fat cells are larger than ordinary. Due to the lack of normal vascularity retrograde changes may occur, such as necrosis followed by calcification. This tumor has been seen in the yellow stock, in which there is a tendency for the mice to become obese. Angiomas.—These are benign and are composed of the elements of either the blood vascular or the lymph circulatory systems. When they are formed from blood vessels they are called hemangiomas, and lymphangiomas when formed from lymph vessels. Hemangiomas grow either as a diffuse mass or as closely clustered groups of endothelial lined spaces supported by a dense stroma. The endothelial. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Roscoe B. Jackson Memorial Laboratory; Little, Clarence C. (Clarence Cook), b. 1888; Snell, George D. (George Davis), 1903-; Dingle, John H. (John Holmes), 1908-. Philadelphia, The Blakiston company


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