. The American journal of roentgenology, radium therapy and nuclear medicine . {0mm., be applied for one hour; 50 Fig. 1. Shows results from ioo mg. for one hour, 50 two hours, 25 mg. for four hours. Radium element ina silver tube, filtered by two layers of gauze and one ofthin rubber. Eight weeks after application. Mostintense reaction was observed about three weeks afterapplication. applied for two hours; and 25 for four hours, in capsules of thesame character, all filtered by 1 mm. leadand a thin sheet of rubber, each separateapplication will amount to 100 , a


. The American journal of roentgenology, radium therapy and nuclear medicine . {0mm., be applied for one hour; 50 Fig. 1. Shows results from ioo mg. for one hour, 50 two hours, 25 mg. for four hours. Radium element ina silver tube, filtered by two layers of gauze and one ofthin rubber. Eight weeks after application. Mostintense reaction was observed about three weeks afterapplication. applied for two hours; and 25 for four hours, in capsules of thesame character, all filtered by 1 mm. leadand a thin sheet of rubber, each separateapplication will amount to 100 , and practically under the sameconditions, yet the effect will be quitedifferent so far as the reaction upon theskin is concerned and likewise its deepeffect must also vary. The 25 four hours will give a more intense 36 The Superficial Reaction of Radium as a Guide to Dosage reaction over a larger field; in other wordsthere will appear to be an accumulativeeffect. The erythema produced by theioo mg. tube will be an oval area about13^ by 2 cm., while the 25 mg. tubewill produce an area of erythema ofabout 2H


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