Fibroids and allied tumours (myoma and adenomyoma) : their pathology, clinical features and surgical treatment . FlGUF Showing the muscle-fibres of a myoma inlongitudinal and transverse in. obj. 3 eyepiece. •AGE 3 I HISTOLOGY 3 its appearance between the tiny growth and the surroundingmuscle, and the identity of the new growth is easily madeout, even when it is only the size of a pins head, by the deepstaining of the muscle-nuclei, which are far more numerousand more closely packed together in the growth than in thesurrounding muscle. Large myomas always show hyaline degeneration ; s
Fibroids and allied tumours (myoma and adenomyoma) : their pathology, clinical features and surgical treatment . FlGUF Showing the muscle-fibres of a myoma inlongitudinal and transverse in. obj. 3 eyepiece. •AGE 3 I HISTOLOGY 3 its appearance between the tiny growth and the surroundingmuscle, and the identity of the new growth is easily madeout, even when it is only the size of a pins head, by the deepstaining of the muscle-nuclei, which are far more numerousand more closely packed together in the growth than in thesurrounding muscle. Large myomas always show hyaline degeneration ; smallones often do the same. Individual muscle-cells are spindle-shaped ; their nucleiare long, narrow, androunded at their muscle-fib re whencut transversely throughits centre appears as aspherical mass of proto-plasm with a central. :ytopl devoid of a nucleus. Fig. i.—Early or seedling myoma composed 11 1 entirely of muscle-cells. A muscle-cell hasno definite size in length and thickness. Mallory statesthat the slowest-growing fibres are the most slender, and heclassifies the fibroids of the clinician under the patho-logical grouping of Leiomyoblastomas (Leiomyomas).^ Leiomyomas are tumours of mesenchymal origin ; thecells tend to differentiate into smooth muscle-cells ; thesegrowths occur not only in the uterus, but in the gastro-intestinal tract, on blood-vessels, in the prostate, and else-where. 1 Mallory, Principles of Pathologic Histology, page 305. MYOMA CHAP. Leiomyomas generally grow slowly, but exceptionallythey take on rapid growth, and the nuclei of the cells thenshow mitotic figures, which is a sign of malignancy. The distinguishing feature between a leiomyoma-celland a fibroma-cell is the presence in the cuticle of theformer of longitudinal striations known as myoglia-fibrils,and to these the deep
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecologyoperative
