. Elements of histology. Histology. 84 Elements of Fig. 58.—From a Lolly itudiual Section of Femur of Rabbit, close to the intermecliate cartilage. a, Calcified cartilage, next to the inter- mediate cartilage; 6,calcified carti- lage covered with thin layer of bone ; c, uiari'ow spaces containing osteoblasts, forming bone on the calcified cartilage; d, niyeloplaxes (chondroclastsj. bones not preformed in the embryo as cartilage are developed directly from the osteogenetic layer of the periostemii in the manner of the i^eri- osteal bone described on p. 80. Here also the new l)one is
. Elements of histology. Histology. 84 Elements of Fig. 58.—From a Lolly itudiual Section of Femur of Rabbit, close to the intermecliate cartilage. a, Calcified cartilage, next to the inter- mediate cartilage; 6,calcified carti- lage covered with thin layer of bone ; c, uiari'ow spaces containing osteoblasts, forming bone on the calcified cartilage; d, niyeloplaxes (chondroclastsj. bones not preformed in the embryo as cartilage are developed directly from the osteogenetic layer of the periostemii in the manner of the i^eri- osteal bone described on p. 80. Here also the new l)one is at first spongy bone, which in its deeper or older layers gradually becomes converted into compact bone. In all instances dm'ing embryonic life and after birth the growth of a bone in thickness takes place after the manner of periosteal or intermem- hranous hone; this is at first spongy, but is gra- dually converted into compact bone. 75. All osseous sub- stance is formed in the embryo and after bii th by the osteoblasts, or marrow cells (Gegenbaur, Wal- deyer) : each osteoblast oivino: orioin to a zone of osseous matrix, and re- maininof in the centre of this as a nucleated ^yo- toplasmic remnant, which gradually becomes branched and transformed into a bone cell. The. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Klein, E. (Edward), 1844-1925; Edkins, John Sydney, b. 1865. Philadelphia : Lea Brothers
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