A text-book of practical therapeutics . thought to .be due both tothe irritation of the stomachand to an effect upon the vomit-ing center in the medulla (Fig. 51), but the large doses of emetinenow used by the hypodermic needle in the treatment of amebicdysentery without producing vomiting wrould seem to prove thatipecac given by the stomach acts on that organ directly. Ipecac iseliminated by the kidneys, the gastro-intestinal mucous membrane,and the skin (Binz). If emetine is given in lethal dose to one of the lower animals, deathis due to failure of respiration, but when it is given by a vei
A text-book of practical therapeutics . thought to .be due both tothe irritation of the stomachand to an effect upon the vomit-ing center in the medulla (Fig. 51), but the large doses of emetinenow used by the hypodermic needle in the treatment of amebicdysentery without producing vomiting wrould seem to prove thatipecac given by the stomach acts on that organ directly. Ipecac iseliminated by the kidneys, the gastro-intestinal mucous membrane,and the skin (Binz). If emetine is given in lethal dose to one of the lower animals, deathis due to failure of respiration, but when it is given by a vein it actsas a powerful cardiac depressant as well. For this reason, if emetineis given intravenously, it should be put in 100 cc of normal saltsolution and injected slowly. Therapeutics.—Ipecac is used as an emetic where a fairly rapidaction is required. It is particularly useful where the stomach of achild is overloaded with food. In cases of poisoning it is hardlyactive or rapid enough as an emetic, and is not so good as mustard or. Fig. 51.—A, vomiting center in the medullasaid to be stimulated by ipecac; B, nerves inmucous membrane of stomach irritated byipecac. 334 DRUGS sulphate of zinc. In babies and young children an attack of bronchitisoften causes digestive disorders by reason of the mucus coughed upfrom the lungs being at once swallowed instead of spat out of themouth. In these cases the stomach may be relieved and the state ofthe lungs improved by the use of an emetic dose of syrup of ipecac,2 to 3 drams (). Often if this dose be not large enough toproduce emesis it will purge the child and remove the mucus by thebowel. In some cases of obstinate vomiting small doses of ipecac will act asa most successful cure, provided that the vomiting is due not to inflam-mation and excitement, but to depression. The proper dose of ipecacfor this purpose is § to J grain () or less every half-houruntil five or six doses are taken. In some cases of the vomit
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Keywords: ., bookcentury1900, bookdecade1920, booksubjecttherape, bookyear1922
