. Kirkes' handbook of physiology . Fig. 45.—A Lobule of DevelopingAdipose Tissue from an Eight-MonthsFetus, a, Spherical or, from pressure,polyhedral cells with large centralnucleus, surrounded by a finely reticrulated substance staining uniformlywith hematoxylin. b, Similar cellswith spaces from which the fat hasbeen removed bv oil of cloves, c. Sim-ilar cells showing how the nucleuswith enclosing protoplasm is beingpressed toward periphery, d. Nucleusof endothelium of investing capilla-ries. (McCarthy.) Drawn by Fig. 46. — Branched Connective-Tissue Corpuscles, Developing intoFat-Ce
. Kirkes' handbook of physiology . Fig. 45.—A Lobule of DevelopingAdipose Tissue from an Eight-MonthsFetus, a, Spherical or, from pressure,polyhedral cells with large centralnucleus, surrounded by a finely reticrulated substance staining uniformlywith hematoxylin. b, Similar cellswith spaces from which the fat hasbeen removed bv oil of cloves, c. Sim-ilar cells showing how the nucleuswith enclosing protoplasm is beingpressed toward periphery, d. Nucleusof endothelium of investing capilla-ries. (McCarthy.) Drawn by Fig. 46. — Branched Connective-Tissue Corpuscles, Developing intoFat-Cells. (Klein.) is always present in some part or other of the cell protoplasm, but in theordinary condition of the loaded cell it is not easily or always visible. Thismembrane and the nucleus can generally be brought into view by extractingthe fat with ether and by staining the tissue. The ultimate cells are held together by capillary blood-vessels, figure 44;while the little clusters thus formed are grouped into small masses, andheld so, in most cases, by areolar tissue. The oily matter contained in thecells is composed chiefly of the compounds of fatty acids with glycerin, olein,stearin, and palmitin. Development of Adipose Tissue. Fat cells are developed from connective-tissue corpuscles. In the infra-orbital connective tissue there are cells ex-hibiting every intermediate gradation between an ordinary branched connec-tive-tissue corpuscle and mature fat cells. Their developmental appearance 38 CELL DIFFERENTIA
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