. Comparative animal physiology. Physiology, Comparative; Physiology, Comparative. I I I I I I ! I >140r 0 . 20 XI :§ 100 i i 140r '. I I I I 60 80-, Cervical sympathetic ^. I 100 60 Sapherjous 0 msec. 20 40 60 80 Fig. 294. After-potentials and excitability cycle following a response, a, after-potential, and b, excitability cycle in cervical sympathetic fibers (cat), c, excitability cycle in saphenous nerve. From Gasser.^°^ Ionic Basis of Nerve Action Potentials. There are few fields of cellular physiology in which it is so difficult to fit the varied chemical and physical observations in
. Comparative animal physiology. Physiology, Comparative; Physiology, Comparative. I I I I I I ! I >140r 0 . 20 XI :§ 100 i i 140r '. I I I I 60 80-, Cervical sympathetic ^. I 100 60 Sapherjous 0 msec. 20 40 60 80 Fig. 294. After-potentials and excitability cycle following a response, a, after-potential, and b, excitability cycle in cervical sympathetic fibers (cat), c, excitability cycle in saphenous nerve. From Gasser.^°^ Ionic Basis of Nerve Action Potentials. There are few fields of cellular physiology in which it is so difficult to fit the varied chemical and physical observations into a reasonable pattern as in nervous propagation. There is little doubt that oxidations supply the recovery energy, probably by restor- ing and maintaining the molecular structure of the plasma membrane. Thia- mine is involved in ;"^^^ Energy appears to be made available by phosphate transfer, as in muscle. A part of the action potential spike consists of reduction in the resting potential, and this probably results from a net increased movement of po- tassium outward, diminishing the ratio of potassium inside to that outside. It has been demonstrated with thin-sheathed nerves (crustacean) that dur- ing propagation the rate of exchange of potassium is greatly increased, with the net effect of an outward movement of potassium.^'^â ''' ^^'''' ~'^^' ^^^ The overshoot whereby the outside becomes negative to the inside may result from siftiultaneous inward movement of sodium.^^^. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Prosser, C. Ladd (Clifford Ladd), 1907-; Bishop, David W. Philadelphia, Saunders
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