. Radium, X rays and the living cell. ^ took the orcein stain strongly. As Unna expressedit, the collagen had become basophile. Gassmann, in investigating the histology of an X-ray ulcer,found in addition to various inflammatory changes, that theendothelial cells lining the larger blood-vessels of the cutis andsubcutaneous tissue had undergone degenerative changes in theshape of swelling and PI,A1E IICHRONIC HYPERTROPHIC RADIO-DERMATITIS, INA CASE OF HUMAN CANCER OF THE THYROIDGtAND, TREATED DURING SEVERAL MONTHS BY X-RAYS. [Dominici, Hcematein Eosin diameters.) SKI


. Radium, X rays and the living cell. ^ took the orcein stain strongly. As Unna expressedit, the collagen had become basophile. Gassmann, in investigating the histology of an X-ray ulcer,found in addition to various inflammatory changes, that theendothelial cells lining the larger blood-vessels of the cutis andsubcutaneous tissue had undergone degenerative changes in theshape of swelling and PI,A1E IICHRONIC HYPERTROPHIC RADIO-DERMATITIS, INA CASE OF HUMAN CANCER OF THE THYROIDGtAND, TREATED DURING SEVERAL MONTHS BY X-RAYS. [Dominici, Hcematein Eosin diameters.) SKIN 171 Lion in 1901 examined sections of healthy skin, which hadbeen subjected to only a shght degree of irradiation and pre-sented no macroscopic changes ; the only histological deviationfrom the normal type was some loosening of the compactpalisade-like layer of the epidermis. An X-ray burn wasdescribed by the same observer as having the epidermal cellsswollen, vacuolated and separated from one another by irregularspaces, while the endothelium of the blood-vessels showed pro-liferation and vacuolation. In 1902 Scholtz published the results of his investigations :the experiments were mostly carried out on young pigs, thoughin some cases rabbits were used. The earlier series of observa-tions were directed to the question of the relative value of hard and soft tubes ; and it was found that the most


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