. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . ilatation cc. 1 100,000 Jugular vein 188-194-164 Marked dilatation cc. 1 10,000 Jugular vein 188-210-168 Marked dilatation cc. 1 1,000,000 Through perfusionfluid None Constriction, verymarked cc. 1 1,000,000 Through perfusionfluid None Constriction, marked cc. 1 10,000,000 Through perfusionfluid None No effect The perfused spleen of this animal dilated with every dose ofadrenahn injected into the jugular vein (fig. 3), but constrictedwith each injection into the perfusion fluid (fig. 4). The latterwa


. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . ilatation cc. 1 100,000 Jugular vein 188-194-164 Marked dilatation cc. 1 10,000 Jugular vein 188-210-168 Marked dilatation cc. 1 1,000,000 Through perfusionfluid None Constriction, verymarked cc. 1 1,000,000 Through perfusionfluid None Constriction, marked cc. 1 10,000,000 Through perfusionfluid None No effect The perfused spleen of this animal dilated with every dose ofadrenahn injected into the jugular vein (fig. 3), but constrictedwith each injection into the perfusion fluid (fig. 4). The latterwas injected into the fluid just before it entered the ,pressure for perfusion was 45 mm. of mercury while thetemperature was °C. The second spleen did not spem to be responding very well andno effect could be obtained except a slight constriction whenadrenalin was introduced into the general circulation. The third perfused spleen, belonging to a dog weighing 10kgm., dilated considerably with the doses of adrenalin injected 422 F. A. HARTMAN AND R. S. LANG. Fig. 3. Dilatation op a Perfused Spleen from the Injection of : 100,000 Adrenalin into the Jugular Vein. Dog 22 kgm.


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