. The elements of pathological histology with special reference to practical methods . s a metastatic tumour. Its cellsmay at first be round and non-pigmented, but later they becomelarger, flatter, and more like endothelial cells, and fill with pigment(Fig. 40). The tumour occurs either in the form of nodes or quitediffusely. The adenoma, which is not uncommonly multiple, occurs in twoforms : as adenoma of the hile-ducts, and as adenoma of the hepatic ADENOMA 261 cells. The former consists of tubes and of bands of cells, which intheir configuration and in the form of their individual cells rec


. The elements of pathological histology with special reference to practical methods . s a metastatic tumour. Its cellsmay at first be round and non-pigmented, but later they becomelarger, flatter, and more like endothelial cells, and fill with pigment(Fig. 40). The tumour occurs either in the form of nodes or quitediffusely. The adenoma, which is not uncommonly multiple, occurs in twoforms : as adenoma of the hile-ducts, and as adenoma of the hepatic ADENOMA 261 cells. The former consists of tubes and of bands of cells, which intheir configuration and in the form of their individual cells recallthe appearance of bile-ducts, from the epithelium of which they haveevidently originated. The liver-celled adenoma, on the other hand,more or less copies in its structure the acinous arrangement of theliver, its cells also corresponding for the most part with the hepaticcells, from which they may probably be derived. The adenomadiffers from carcinoma above all in its sharp delimitation from thehepatic tissue, which may even find expression in the presence of afibrous capsule. /^. Fig. 130.—Primary Glandular Carcinoma of the Liver, originating in the bile-ducts. X 240. (Hajmatoxylin and eosin.) o, Capsule of Glisson ; 6, Portal vein ;c. Bile-ducts, partly in proliferation ; d. Small-celled infiltration of the hepatic connec-tive tissue at the edge of the carcinoma ; e, Hepatic cells with fat-drops ; /, Atrophiedand pigmented hepatic cells ; (j. Solid cylinders of cancer cells ; /i, Tubes of cancer cells,with partially cylindrical elements and lumen filled with desquamated and partlynecrotic cancer cells; i, Connective-tissue stroma of the carcinoma, with spindle cells. Cysts may form in the liver from the vasa aberrantia of the bile-ducts, owing to accumulation of the secretion derived from their 262 THE LIVER mucous glauds. They are lined either with flat- or cylinder-celledepithelium, the latter either with or without cilia. Carcinoma occurs both primarily and (much more


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895