Granulomatosis with polyangiitis


Petechial lesions on the abdomen of a 69 year old Hispanic male patient with granulomatosis with polyangiitis (GPA). These small spots are due to minute haemorrhages. GPA, also known as Wegener's granulomatosis, is a form of vasculitis (inflammation of blood vessel walls) that mainly affects the upper airways, lungs and kidneys. This causes a lack of blood flow that can lead to the formation inflammatory lesions (granulomas). The cause of PGA is not known. Due to its end-organ damage, it can be a serious disease that requires long-term immune suppression as treatment.


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Photo credit: © RICHARD USATINE MD / SCIENCE PHOTO LIBRARY / Alamy / Afripics
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