The Cleveland medical journal . ing reaction for amyloidcould be obtained. In this region no osseous or osteoid tissuewas found. The intima over the upper portion of this plaque hasdisappeared and the thrombus lies in intimate association with theinner portion of the media. Sections from just below this shelfshow a most interesting structure. The adventitia is greatly thick-ened and traversed by numerous small vessels. The tissue stainsquite well, but with VerhofTs stain the elastic fibers are seen to bebroken and degenerated. In the media by the same stain evengreater degeneration of the elas
The Cleveland medical journal . ing reaction for amyloidcould be obtained. In this region no osseous or osteoid tissuewas found. The intima over the upper portion of this plaque hasdisappeared and the thrombus lies in intimate association with theinner portion of the media. Sections from just below this shelfshow a most interesting structure. The adventitia is greatly thick-ened and traversed by numerous small vessels. The tissue stainsquite well, but with VerhofTs stain the elastic fibers are seen to bebroken and degenerated. In the media by the same stain evengreater degeneration of the elastic fibers is found. In fact, inmost of the sections elastic tissue can be seen only as smallstrands. The media is considerably thickened and in those por-tions not invaded by large collections of calcium salts, the cellsare found greatly changed in both size and shape, and the nucleistain poorly. The cytoplasm takes an irregular basic stain;numerous cells are found containing dust like basic staining ma-terial (calcium salts).. Fig. 4. Modified connective tissue at A, marrow at B. Hematoxylin and eosin x 79. Around one-half of the vessel in a crecentic formation, partlyin the media and partly in the intima, there is found an area, com-posed of osseous tissue with large narrow spaces containing redmarrow in which all types of marrow cells can be found. In allsuch places there are also large collections of calcium deposits inthe immediate neighborhood. This structure is well shown inFigures (1) and (2). Figure (3) is a microphotograph of higher 732 The Cleveland Medical Journal magnification than (1) and (2) and in it can be seen the true boneand its relation to the marrow. The bone shows a definite lamellarstructure and numerous typical bone corpuscles. With still greatermagnification a layer of cells more or less distorted and which re-semble osteoclasts can be found forming a membrane coveringthe edges of the osseous tissue. Figure (4) shows the interme-diate stage of the met
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectmedicine, bookyear191
