Rabies Virus, LM
Photomicrograph demonstrates cellular changes associated with rabies encephalitis using an H&E staining technique. When brain tissue from rabies virus-infected animals are stained with a histologic stain, such as hematoxylin and eosin, evidence of encephalomyelitis may be recognized by a trained microscopist. The virus infects the central nervous system, causing encephalopathy and ultimately death. Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-sense single-stranded RNA ((-) ssRNA) genomes. Early symptoms of rabies in humans are nonspecific, consisting of fever, headache, and general malaise. As the disease progresses, neurological symptoms appear and may include insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, agitation, hyper-salivation, difficulty swallowing, and hydrophobia (fear of water). Death usually occurs within days of the onset of symptoms.
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Photo credit: © Photo Researchers / Alamy / Afripics
License: Licensed
Model Released: No
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