. Biology of Peromyscus (Rodentia). Mice; Peromyscus. < 14 CD 10 Eu(l()( liiiology -il'i P. m. ba i rd i • NORMAL X THYROIDECTOMIZED gracilis o NORMAL D THYROIDECTOMIZED. 0 5 10 15 20 30 40 AGE IN DAYS 50 60 70 Fig. 7. Per cent proteins in the brain of two subspecies of deermice during growth and maturation under normal conditions and after thyroidectomy. (From Elefthcriou, 1961.) absorb the nutrients transported in the blood stream which are essential for protein synthesis; this could explain the irreversibility of retarded mental and behavioral development in cretins and hypothyroid
. Biology of Peromyscus (Rodentia). Mice; Peromyscus. < 14 CD 10 Eu(l()( liiiology -il'i P. m. ba i rd i • NORMAL X THYROIDECTOMIZED gracilis o NORMAL D THYROIDECTOMIZED. 0 5 10 15 20 30 40 AGE IN DAYS 50 60 70 Fig. 7. Per cent proteins in the brain of two subspecies of deermice during growth and maturation under normal conditions and after thyroidectomy. (From Elefthcriou, 1961.) absorb the nutrients transported in the blood stream which are essential for protein synthesis; this could explain the irreversibility of retarded mental and behavioral development in cretins and hypothyroid animals. The influence of hypothyroidism upon enzymes of the cerebral cortex has been found to result in reduction of several oxidative enzymes of the tricarboxylic acid cycle (Hoff- man and Zarrow, 1958). Such extensive research has not been carried out with members of the genus Peromyscus. However, data on normal development and development after radiothyroidectomy at birth of certain brain constituents have been gathered on two subspecies, gracilis and bairdi (Eleftheriou, 1961; Rawson and Money, 1949). It has been found that gracilis, the larger of the two, has a significantly greater brain weight than bairdi as early as 15 days of age. The adult brain weight of gracilis reaches an average maximum of 584 milligrams whereas bairdi attains a brain weight of 470 milligrams (Fig. 6). In spite of this difference in weight between the two subspecies, it has been found that on a per cent basis, the deposition of total solids, proteins (Fig. 7), lipids (Fig. 8), and cholesterol is signif- icantly earlier in bairdi than in gracilis, and neurokeratin content. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original King, John Arthur, 1921-. [Stillwater, Okla. ] American Society of Mammalogist
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