. The Biochemical journal, 1917. Biochemistry. TUMOUR AND NORMAL TISSUE GROWTH 341 It will be seen from Chart 3 that this diet is adequate to supply the nutri- tive requirements of the rat throughout its life cycle. Tumour development proceeds at an equally normal rate in hosts fed upon this dietary, and is not accompanied by a loss in weight of the animal itself, until secondary disturbances, such as an ulceration of the tumour with resulting sepsis, set in. Rat Days 12 19 26 33 40 R«ui«rti« Weight of tutnuur 1! Weight of rat-lumuui g Thange in wt:i{;lil ot ml g Chujge weigh 1 ufral per Ig tu
. The Biochemical journal, 1917. Biochemistry. TUMOUR AND NORMAL TISSUE GROWTH 341 It will be seen from Chart 3 that this diet is adequate to supply the nutri- tive requirements of the rat throughout its life cycle. Tumour development proceeds at an equally normal rate in hosts fed upon this dietary, and is not accompanied by a loss in weight of the animal itself, until secondary disturbances, such as an ulceration of the tumour with resulting sepsis, set in. Rat Days 12 19 26 33 40 R«ui«rti« Weight of tutnuur 1! Weight of rat-lumuui g Thange in wt:i{;lil ot ml g Chujge weigh 1 ufral per Ig tumour 9 6 9 9 9 d •iff • #••• •fit • • ••• • • t • f # • • • • Tuiiiuur Hnn and solid Slight central necrosis Animal died 17 Tumour Hrm Ceulral necrosis Tumour retrogressed 107 255 6 7 240 160 lli3 140 5 1413 1460 1270 + 173 + 405 4 55 3 + 55 0 + 42 0 Average 166 - + 42 0 + 2 5. Normal flat ^ ^ —^ fiat - Tumow HbI * lumoiir X Inoculated Y youn^ Botit // // // Chart .3. Tumour development, and growth curves of normal and tumour-bearing rats upon a complete artificial dietary. Tumour S/l'2Qd. Diet: Caseinogen, 18 %, Starch, 40 %. Agar, 3%, Salt Mixture, o %, "Yeast preparation " 6%, butter-fat, 20%. As has already been stated, Osborne and Mendel [1915, 1] found that when the caseinogen content of such a diet as the above was lowered, a stage. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Biochemical Society (Great Britain); University of Liverpool. Biochemical Dept. London [etc. ] Cambridge University Press
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbiochem, bookyear1917