Studies in blood-pressure : physiological and clinical . y allthe cases of diphtheria in the Edinburgh CityHospital were by routine practice put upon strych-nine and alcohol on admission, the fall of blood-pressure due to the toxiccondition was to a largeextent annulled. In cases which did not receiveany such stimulant a fall was in every case noteduntil this treatment was commenced. During theroutine administration of such stimulants overlong periods, the blood-pressure response to anysingle dose was apparently absent, or in any casewas much less marked than that following thefirst few doses


Studies in blood-pressure : physiological and clinical . y allthe cases of diphtheria in the Edinburgh CityHospital were by routine practice put upon strych-nine and alcohol on admission, the fall of blood-pressure due to the toxiccondition was to a largeextent annulled. In cases which did not receiveany such stimulant a fall was in every case noteduntil this treatment was commenced. During theroutine administration of such stimulants overlong periods, the blood-pressure response to anysingle dose was apparently absent, or in any casewas much less marked than that following thefirst few doses given to the patient; but in thesecircumstances, if the routine order were suspendedfor one or two periods, the blood-pressure wasnoticed to be affected. This constant blood-pressure level, as maintained by the use of strych-nine at regular intervals, seems to represent theideal to be aimed at in the stimulant treatment oftoxic conditions such as diphtheria. J 1 Blood-Pressure in Fevers, by James Davidson, , etc.,The Lancet, vol. ii, 1907, p. Fig. 6.—The Arteriometer. (Full-size.) Thearteriometer is made by Mr. Hawksley, 357 Oxford Street, London, W, CHAPTER X ON ARTERIOMETRY Having found the calibration of the radial arteryuseful and instructive when made by the side ofblood-pressure measurements, I will describe thelittle instrument (Fig. 6) which I devised someyears ago for the purpose of determining the internaldiameter or calibre of the artery. It is applied inthe vertical position, at right angles to theartery and to the arm (see Fig. 7). Each observa-tion comprises two stages. In the first the pointerand the dial travel for a certain distance, whichvaries in each case, from right to left—then the dialceases to move. In the second stage the pointersuddenly leaves the stationary zero and travelsfrom left to right—in the direction of the arrow onthe dial. During this second stage the artery isbeing closed, and the excursion of the pointerfrom zero to t


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