American journal of physiology . ^oth-esis is more or less plausible. Increase of rate may cause decrease ofdepth by not allowing time for the completion of expiration; the ratein this case would be the cause and the shallow breathing the of depth, on the other hand, by securing more perfect alveolarventilation may delay the adequate stimulus to increase of rate; in 378 Theodore this case the deep breathing would be the cause and the slow rate theresult. Or it may well be that in different experiments or during dif-ferent periods of the same experiment either one may be


American journal of physiology . ^oth-esis is more or less plausible. Increase of rate may cause decrease ofdepth by not allowing time for the completion of expiration; the ratein this case would be the cause and the shallow breathing the of depth, on the other hand, by securing more perfect alveolarventilation may delay the adequate stimulus to increase of rate; in 378 Theodore this case the deep breathing would be the cause and the slow rate theresult. Or it may well be that in different experiments or during dif-ferent periods of the same experiment either one may be a determiningcause of the other. It has been shown that in those cases which showa horizontal or downward trend of the base line we have convincing evidence of distinct expira-tory activity, with highefficiency of alveolar ven-tilation, and in all thesecases the rate is kept downor even depressed. Yet,even here, one cannot saywhether the low rate is thedirect result of the moreperfect ventilation, or Figure 5. — Graphic representation of the types of whether the inadequacy ofchange of expiratory base line. Type 1 is shown by the Stimulus tO increased1 subject out of 25 (J Type 2 is shown ^^^^ ^^^^^ ^^^^^^^ ._ by 1 subject out of 25 (J. B. S.). Type 3 is shown , by 14 subjects out of 25. Type 4 is shown by 6 le more complete ex^pira-subjects out of 25. T>-pe 5 is shown by 2 subjects


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