Studies from the laboratories of the Deptof Surgery . The process is similar to that found in any bune transplant;gradual absorption and deposition of new hone occurring throughout theHaversian canals until all the dead bone has l)cen replaced. I have emphasized these facts because I believe they have a detiniteinfluence on human surgery. I shall show in the study of clinical casesthat in children bone tissues that are apparently dead can be saved to advantage. During the last five vears we have had eleven cases of acute osteo-myelitis in children on Doctor Pools service at the New York Hospit
Studies from the laboratories of the Deptof Surgery . The process is similar to that found in any bune transplant;gradual absorption and deposition of new hone occurring throughout theHaversian canals until all the dead bone has l)cen replaced. I have emphasized these facts because I believe they have a detiniteinfluence on human surgery. I shall show in the study of clinical casesthat in children bone tissues that are apparently dead can be saved to advantage. During the last five vears we have had eleven cases of acute osteo-myelitis in children on Doctor Pools service at the New York has been possible to follow these cases and to observe the results of 683 FREDERIC \V. BANCROlT treatment. Trauma was the most prominent etiological factor in ourseries. Six or (.)0 per cent, received injuries varyinq- from ten hours totwo weeks before the onset of the acute process. That trauma and thepresence of bacteria in the blood-stream can cause ostet)ni\ clitis in animalshas been demimstrated bv Lexer and others. We ha\e produced it in. ^-v Pig. 4 (Path. .No. ^MS).—Microscopic section. In the lowei zone of separation necroticdi-bris disappeared during decalcification. .Slj, sequestrum; In, involucrum; 5, separa-tion zone. rabbits in the Surgical Jvesearch Laboratory by traumatizing the legwithout breaking the skin, and injecting into the veins of the ear a strainof staphylococcus from a case of human osteomyelitis, which had sub-sequently been transmitted through rabbits. On sectioning the femur,which had been fractured by the force of the blow, there was a marked 684 ACUTE H.^MATOGENOUS OSTEOMYELITIS
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