. Gynecological pathology; a manual of microscopic technique and diagnosis in gynecological practice, for students and physicians. the epitheliumof the glands, but recent investigation has shown that they may de-velop from the cylindrical epithelium of the surface. The connective-tissue neoplasms (sarcoma) develop from the cells of the interstitialtissue. (a) Carcinoma of the Endometrium. For the diagnosis of carcinoma of the uterine mucosa, which is of lessfrequent, occurrence than that of the vaginal portion of the cervix, thesame rules hold good as for the latter. It would, therefore, be a
. Gynecological pathology; a manual of microscopic technique and diagnosis in gynecological practice, for students and physicians. the epitheliumof the glands, but recent investigation has shown that they may de-velop from the cylindrical epithelium of the surface. The connective-tissue neoplasms (sarcoma) develop from the cells of the interstitialtissue. (a) Carcinoma of the Endometrium. For the diagnosis of carcinoma of the uterine mucosa, which is of lessfrequent, occurrence than that of the vaginal portion of the cervix, thesame rules hold good as for the latter. It would, therefore, be a repeti- CARCINOMA OF THE ENDOMETRIUM. 101 tion were I to mention again these various points. A carcinoma is al-ways (sometimes with modifications in structure, such as cancroid, col-loid carcinoma) a formation of epithelioid elements in a connective-tissuebasis. The boundaries of the remaining tissue are not respected by theneoplasm, for the latter grows, in atypical form, into the glands andvessels without stopping at their enveloping membrane. A piece ofcuretted mucous membrane is sufficient for this diagnosis, for in the. Figure 37.—Carcinoma of the , gland sections with growth of epithelium ; ft, carcinoma nodules ; d, interstitial tissueconsisting of spindle cells, between which scattered round cells are found. mucous membrane are various tissues from which we may easily see thevariations of a neoplasm if the structure of this neoplasm is fully pro-nounced. No one can hesitate to recognize in Fig. 37, a curetted particle,the presence of a carcinoma. The drawing presents several very important and characteristic see the easily recognized cancer area (o) and also changed these cancer cones we recognize epithelioid cells of various the lighter color of the drawing shows, they have taken on the hema- 102 CARCINOMA OF THE ENDOMETRIUM. toxylin stain less intensely than the remaining tissue and the cells liningthe glands. The sharply out
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