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. Electronic apparatus for biological research . Carrier of stereotaxic instrument Sealing wax Spring ^y^-lead Insulation ^^^Electrode tip Figure Sprung electrode base the electrode will bend the spring before the electrode breaks and this is particularly useful if the tip of the electrode is situated near the skull floor. When electrodes have to be implanted and left in situ for long periods, for example during investigations of the effect of stimuli on conscious animals, the reaction of the tissues to the presence of the electrode must be considered. Any strong tissue reaction will caus
. Electronic apparatus for biological research . Carrier of stereotaxic instrument Sealing wax Spring ^y^-lead Insulation ^^^Electrode tip Figure Sprung electrode base the electrode will bend the spring before the electrode breaks and this is particularly useful if the tip of the electrode is situated near the skull floor. When electrodes have to be implanted and left in situ for long periods, for example during investigations of the effect of stimuli on conscious animals, the reaction of the tissues to the presence of the electrode must be considered. Any strong tissue reaction will cause the electrode to become surrounded by inflammatory cells which will alter markedly the relationship of the electrode to the normal tissues. Chronically implanted electrodes should be as far as possible both chemically and mechanically inert. Platinum and gold satisfy these requirements but gold is too soft for general purposes. Most chronically imbedded electrodes are made of platinum or platinum-iridium alloy, although stainless steel, tungsten and silver are also employed. Silver may give rise to black deposits in the tissues after several weeks (Harris^) which are probably silver sulphide. The surface of an implanted metal electrode should be carefully polished before insertion to eliminate roughness, and the insulating material must be non-toxic and as far as possible non-irritant to tissues. It is an added 571
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Keywords: ., bookcentury1900, bookcollectionameri, bookcollectionbiodiversity