. Gynecology : . t incutting the section. The lower part of the section is the cortex of the ovary, the epithelial coveringbeing absent. degenerates and disappears. This process is termed atresia of the follicle, andis, in a certain sense, physiologic. Atresia of a follicle is attended with a certainamount of secretion, especially when the lining epithelium (granulosa) persists, NEW GROWTHS 383 so that many of the follicles become visible cysts of greater or less cyst formation is, within certain limits, to be regarded as a physiologicprocess. Under certain conditions, however,
. Gynecology : . t incutting the section. The lower part of the section is the cortex of the ovary, the epithelial coveringbeing absent. degenerates and disappears. This process is termed atresia of the follicle, andis, in a certain sense, physiologic. Atresia of a follicle is attended with a certainamount of secretion, especially when the lining epithelium (granulosa) persists, NEW GROWTHS 383 so that many of the follicles become visible cysts of greater or less cyst formation is, within certain limits, to be regarded as a physiologicprocess. Under certain conditions, however, the production of these cystsbecomes abnormally great, and the ovary is then said to be in a state of cysticdegeneration, though the line between the normal and abnormal state is notclearly defined. Just what causes cystic degeneration is a matter of somedoubt. Increased density of the connective-tissue stroma (interstitial oophori-tis), which prevents proper resorption of the atretic follicle elements, probably. Fig. 134.—Cyst of a Graafian power. At the top is the lining of the cyst wall, consisting of layers of cells derived fromthe membrana granulosa of the follicle. Below this is the loose connective tissue that surrounds thefollicle, and below this the dense connective tissue of the cortex of the ovary. acts as a cause in a certain number of cases. In other instances it is likely thatdisturbances of circulation, such as repeated or continuous hyperemia, maycause a too rapid development of the primordial follicles and hence an over-production of atretic follicles. Cystic degeneration causes a general enlargement of the ovary, but it doesnot reach the dignity of a tumor until one of the cysts grows at the expenseof the other cysts and the rest of the ovarian tissue. The growth of an atretic follicle cyst may be due to persistence of the lining 384 GYNECOLOGY epithelium which continues to secrete a clear amber fluid (v. Franque). Usually,however, the membran
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