The Journal of nervous and mental disease . ? ? The fewest large and small pyramid cells show well-defined processes. The contours are rounded, and thecell substance exhibits every possible change of its proto-plasmatic substance. In some there are a distinct nucleusand nucleolus, surrounded by a detritus-like mass; in many ARRESTED CEREBRAL DEVELOPMENT. 551 the nucleus and nucleolus are entirely wanting. All thesevaried changes can be studied best with the acid fuchsinmethod ; in Weigert preparations, the whole pathologicalcell mass takes up the stain deeply, and it is not alwayseasy to disti


The Journal of nervous and mental disease . ? ? The fewest large and small pyramid cells show well-defined processes. The contours are rounded, and thecell substance exhibits every possible change of its proto-plasmatic substance. In some there are a distinct nucleusand nucleolus, surrounded by a detritus-like mass; in many ARRESTED CEREBRAL DEVELOPMENT. 551 the nucleus and nucleolus are entirely wanting. All thesevaried changes can be studied best with the acid fuchsinmethod ; in Weigert preparations, the whole pathologicalcell mass takes up the stain deeply, and it is not alwayseasy to distinguish the nucleus and cell-body. Glancingthrough the sections, you will also observe that a few ofthe cells turn their apices downward instead of upward,thus exhibiting a change to which Bruckner refers as oc-curring in his case of tuberous sclerosis and to which nopathological significance is to be attached. Plate III. exhibits these changes under a very muchhigher power. In some cells a partly normal and a partlypathological charact


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic