Pathology and treatment of diseases of women . ic features, suchas metaplastic epithelial proliferation, infiltrating growth, formation ofmetastases, can be proven in all cases by a thorough examination. According to our view-point the conception of adenoma malignummust be dropped. Corpus carcinomata may appear in the beginning as circumscribed(especially those which develop on a basis of mucous polypi—see Figs. 276 DISEASES OF WOMEN 130 and 131), or as diffuse in a large area of the mucosa of the corpus(see Fig. 132). In these also a superficial disintegration takes place,although, for reason
Pathology and treatment of diseases of women . ic features, suchas metaplastic epithelial proliferation, infiltrating growth, formation ofmetastases, can be proven in all cases by a thorough examination. According to our view-point the conception of adenoma malignummust be dropped. Corpus carcinomata may appear in the beginning as circumscribed(especially those which develop on a basis of mucous polypi—see Figs. 276 DISEASES OF WOMEN 130 and 131), or as diffuse in a large area of the mucosa of the corpus(see Fig. 132). In these also a superficial disintegration takes place,although, for reasons still to be discussed, it occurs later than in the caseof carcinomata of the cervix. The behavior toward the supporting tissue of the mucosa, respectivelythe fibromuscular tissue of the uterine wall, is common to all the describedforms of uterine carcinoma. As in most of the carcinomata the support-ing tissue is gradually rarefied and finally entirely displaced by the ad-vancing tumor. Especially the adenomatous carcinomata are character-. iJT- Fig. 129.—Carcinoma Adenomatosum Corporis Uteri. (Authorspreparation. Zeiss, Obj. A A, Oc. 4.) ized by their exceedingly delicate, intraglandular connective-tissue tracts,,often consisting only of a single cell layer, while in the cauliflower growthand in many carcinomata occurring in the scirrhus form (so-called wormycarcinomata, C. Ruge) the connective tissue takes a larger part in thetumor formation. All around the margin of the malignant tumor the sup-porting tissue is found in a condition of an exceedingly dense round cellinfiltration, which, according to our present conception, is probably tobe looked on as an expression of a hopeless fight of the organism againstthe advancing enemy. We have already referred to the peculiar tendency of uterine carcino-mata to superficial disintegration. The result of this peculiarity is thatthe necrotic tumor-masses offer an excellent culture medium for the PATHOLOGY OF THE VAGINA AND UTERUS
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