The principles and practice of surgery: embracing minor and operative surgery : with a bibliographical index of American surgical writers from the year 1783 to 1860 : arranged for the use of students (Volume 2) . ese de-posits are produced. Invariably the depositis the consequence of the appearance in theurine of some acid capable of decomposingthe soluble urates, this being probably inmost cases Lactic Acid, which is frequentlydeveloped in healthy urine after it has beenpassed some hours. This, uniting with thebases, forms lactates, setting the uric acidfree. Acetic acid is probably developed
The principles and practice of surgery: embracing minor and operative surgery : with a bibliographical index of American surgical writers from the year 1783 to 1860 : arranged for the use of students (Volume 2) . ese de-posits are produced. Invariably the depositis the consequence of the appearance in theurine of some acid capable of decomposingthe soluble urates, this being probably inmost cases Lactic Acid, which is frequentlydeveloped in healthy urine after it has beenpassed some hours. This, uniting with thebases, forms lactates, setting the uric acidfree. Acetic acid is probably developed, attimes, in the same manner, and produces thesame results. This process, which in healthyurine does not usually commence for severalhours after the urine is passed, is designatedby Scherer as the acid or sour fermentationof the urine, to distinguish it from the alkaline fermentation which sets inlater, and which will be described in connection with the etiology of phos-phatic deposits. The acid fermentation and consequent precipitation of uric acid, whichnominally does not take place for some hours after the urine is passed, may,in consequence of constitutional or local conditions which are not yet com-. Crystals of Uric Acid. (After Bird.) SEDIMENTS OF THE URATES. 505 pletely understood, occur preternaturally early, beginning immediately afterthe urine is passed, or even before it is voided, in the bladder, or, in extremecases, in the kidneys. It is, of course, only in these latter cases, in whichthe uric acid is precipitated in a crystalline form in the body, that there isdanger of the formation of calculi. It will then be perceived that the condition determining the precipitationof the uric acid is the preternatural acidity of the urine, and not any excessof the uric acid itself. Indeed, deposits of uric acid, if the urine be unnatu-rally acid, may occur in cases in which the total quantity of uric acid passedin the twenty-four hours is actually diminished; and conversely,
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