. The practice of pediatrics. m Fig. 67.—Amaurotic idiocy. (Early stage.) whose origin is not understood, has been attributed to syphilis and al-cohol. The pathologic findings prove the disease to be due to a toxemiawhich slowly but persistently attacks and entirely destroys, throughdegenerative processes, whatever is vital in the entire nervous —Consistence is again shown in the lesions of the disease,which, wherever present, are invariably the Fig. 68.—Amaurotic idiocy. Same case. (Late stage.) Hirschs early findings have been corroborated by many others,showing that
. The practice of pediatrics. m Fig. 67.—Amaurotic idiocy. (Early stage.) whose origin is not understood, has been attributed to syphilis and al-cohol. The pathologic findings prove the disease to be due to a toxemiawhich slowly but persistently attacks and entirely destroys, throughdegenerative processes, whatever is vital in the entire nervous —Consistence is again shown in the lesions of the disease,which, wherever present, are invariably the Fig. 68.—Amaurotic idiocy. Same case. (Late stage.) Hirschs early findings have been corroborated by many others,showing that there is a degeneration of the ganglion cells throughoutthe entire nervous system. If we are to believe these investigations,there is not a normal cell left either in the cortex or the gray matter ofthe cord. The cell protoplasm undergoes degeneration, the nucleus is demon- AMAUROTIC FAMILY IDIOCY 491 strable with difficulty and becomes a part of the degenerated changes cause an entire loss of cell structure and render it difficultto determine the cell contour. The ganglion-cells of the retina and the fibers of the optic nervesand tracts are degenerated, this fact accounting for the of the white fibers of the anterior and lateral pyramidaltracts has been described by Shaffer. Sachs is of the opinion that theseare secondary changes. The thoracic and abdominal viscera show no specific lesions. Symptoms.—The history is usually
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Keywords: ., bookcentury1900, bookdecade1910, bookid39002, booksubjectchildren
