General therapeutics and materia medica (volume 1): adapted for a medical text book . moderntimes has been brought forwardas a substitute for cinchona. Itwould seem to accord most inproperties with willow bark,—the latter appearing, however, tobe more effective, and to agreebetter with the digestive was much used during thewars of Napoleon, when cincho-na was scarce. It has, likewise,been administered as an astrin-gent tonic when such an agentwas indicated. Many of theEuropean pharmacopoeias havean aqueous extract of the bark,which is said to agree better withthe stomach than the pow


General therapeutics and materia medica (volume 1): adapted for a medical text book . moderntimes has been brought forwardas a substitute for cinchona. Itwould seem to accord most inproperties with willow bark,—the latter appearing, however, tobe more effective, and to agreebetter with the digestive was much used during thewars of Napoleon, when cincho-na was scarce. It has, likewise,been administered as an astrin-gent tonic when such an agentwas indicated. Many of theEuropean pharmacopoeias havean aqueous extract of the bark,which is said to agree better withthe stomach than the powder ordecoction. The following Factitious Pow-der of Bark is contained in thePrussian Pharmacopoeia : — Hippocast., Cort. Salicis,Cort. Gentian, rubr., Caryophyll. aa. 3ij.—M. In this preparation, the willow—asalready remarked—has medical virtues analogous to those of horse-chestnut bark; gentian is a simple bitter; and calamus and cloves areexcitants. Hufeland affirms, that this powder is an adequate substitutefor cinchona in three cases in jEsculus Flower, b. Fruit. 69. NARCOTINA.—NARCOTIN. Narcotin is obtained either from the aqueous extract of opium of theshops by means of ether, which dissolves only the narcotin, and con-sequently requires only to be evaporated to obtain it; or from crudeopium, which has been exhausted by cold water. Narcotin crystallizesin white needles; is devoid of taste and smell; neutral; and, of course,very soluble in ether. It is also soluble in hot alcohol. As elsewhere remarked, narcotin was supposed to be the excitantproperty of opium; morphia the sedative ; but subsequent researcheshave not established this. Although it is insipid, its salts are intensely bitter. The sulphate andthe muriate have been used as antiperiodics,—the latter with great suc-cess. The following is the mode of preparing the latter salt, whichwas employed by Dr. OShaughnessy in India as a substitute for quinia. CE


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