Gynecology . l tissue as to its malignancy, because destruction of the maternal tissue is the most importantfunction of the trophoblast. (Translation.) Symptoms.—Chorio-epithelioma usually makes itself known by repeateduterine hemorrhages following an abortion or a mole. Bleeding is always thecharacteristic symptom, no matter where the tumor is located, and is due to thecorrosive action of the tissue on the walls of blood-vessels with which it comes 318 GYNECOLOGY in contact. Cureting brings about only a temporary cessation of the bleeding,which is apt to be severe and depleting. The patient b
Gynecology . l tissue as to its malignancy, because destruction of the maternal tissue is the most importantfunction of the trophoblast. (Translation.) Symptoms.—Chorio-epithelioma usually makes itself known by repeateduterine hemorrhages following an abortion or a mole. Bleeding is always thecharacteristic symptom, no matter where the tumor is located, and is due to thecorrosive action of the tissue on the walls of blood-vessels with which it comes 318 GYNECOLOGY in contact. Cureting brings about only a temporary cessation of the bleeding,which is apt to be severe and depleting. The patient becomes rapidly anemicand cachectic. Albuminuria is a very frequent accompaniment. A secondcureting reveals a new mass of tissue in the canal of the uterus. A diagnosis bymicroscopic examination of the curetings is very difficult to make, as is explainedabove, and patients are often lost as a result of a negative report from thepathologist. It is extremely necessary, therefore, to take into account the clin-. Fig. 118.— power. At the bottom is the edge of a chorionic villus covered with a regular layer of Lang-hans cells. In the middle, lying on this, is syncytium. To the left of this and above it are masses ofLanghans cells. Near the top and near the right edge are large fragments of syncytium having thelarger, deeper staining nuclei and deeper staining protoplasm, the whole floating in blood. ical course of the disease, without relying too much on the findings of the micro-scope. After metastases occur the diagnosis is simple, but it is then usually toolate for treatment, though cases of spontaneous cure even at this stage have beenreported. Metastases frequently occur in the vagina, and sometimes the first evidenceof the disease is seen here, the chief symptom being bleeding. On account of thecorrosive action of the tumor and the friability of its tissue, metastatic emboli NEW GROWTHS 319 slip very readily into the blood-stream and are carried to dis
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