. The Journal of laboratory and clinical medicine . dered anaerobic Avhile the top necessarilyremains aerobic and the space betAveen represents a gradient of oxygen pres-sure intermediate betAveen the tAvo extremes. He has further observed,The infecting organism may be sensitive to oxygen pressure. In this man- 540 THE JOURNAL OF LABORATORY AND CLINICAL MEDICINJE ner bacteria that are sensitive to sliglit changes in oxygen pressure may begroAvu. We have been able to grow strict anaerobes in this medium. In our series of 213 cases the blood and spleen were cultured routinely;the spleen was cult
. The Journal of laboratory and clinical medicine . dered anaerobic Avhile the top necessarilyremains aerobic and the space betAveen represents a gradient of oxygen pres-sure intermediate betAveen the tAvo extremes. He has further observed,The infecting organism may be sensitive to oxygen pressure. In this man- 540 THE JOURNAL OF LABORATORY AND CLINICAL MEDICINJE ner bacteria that are sensitive to sliglit changes in oxygen pressure may begroAvu. We have been able to grow strict anaerobes in this medium. In our series of 213 cases the blood and spleen were cultured routinely;the spleen was cultured in order to determine if it acted as a bactericidalfactor or as a filter for organisms. Other systems, chiefly the genitourinary,respiratory, and cerebrospinal systems, were cultured as conditions demanded. Bearing in mind the fact that infected foci may be the source of generalinfections, and, as many writers have pointed out, may be the cause of certaindiseases, we cultured teeth which were condemned by dental examinationsmade before The relative pathogenicity of organisms recovered and their significanceas the cause of certain lesions can best be established by animal have therefore resorted to this procedure in obscure cases, using rabbitsand other laboratory animals. The bodies used were not subjected to refrig-eration, but were exposed to the temperature prevailing in summer or winterand for the periods of time indicated in Fig. 1. GAvyn and Harris have compared antemortem and postmortem culturesin fourteen cases with a view to determining the reliability of postmortemcultures. In seven cases the agreement is absolute; two cases shoAv the pres-ence of an additional organism after death due to a superadded termiiuilinfection; and five cases show radical differences in antemortem and postmor- POSTMORTEM BACTERIOLOGY 541 tern results. Riehey and Goehring report tAventy-four cases in which bothantemortem and postmortem cultures were made, in twenty
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