. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. Vh= -80 mV \r pQFYRFa j nA 10s Figure 7. Comparison of currents evoked by FMRFamide and pQFYRFamide in the C2 neuron. At a holding potential of -45 mV. pQFYRFamide evoked an outward current, whereas FMRFamide evoked a fast inward current. Even at -80 mV, close to the reversal potential for the potassium response, no inward current in response to pQFYRFamide was seen. Identical results were obtained in experi- ments in which the order of application was reversed (not shown). The ami no acid segments that are processed to
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. Vh= -80 mV \r pQFYRFa j nA 10s Figure 7. Comparison of currents evoked by FMRFamide and pQFYRFamide in the C2 neuron. At a holding potential of -45 mV. pQFYRFamide evoked an outward current, whereas FMRFamide evoked a fast inward current. Even at -80 mV, close to the reversal potential for the potassium response, no inward current in response to pQFYRFamide was seen. Identical results were obtained in experi- ments in which the order of application was reversed (not shown). The ami no acid segments that are processed to be- come the individual mature peptides are not distributed at random in the precursors, rather, they are clustered according to their sequences in two domains. First, the C-terminal end of the precursor (always downstream of the tetrabasic sequence, ) is the site of repeated segments, each comprising a FMRF sequence with its processing signals and acidic spacers. Second, the N-ter- Vh= -45 mV pQFYRFa B mM K- | nA 2s 5 mM K- -120 -100 -60 -40 Vh (mV) -20 > L Figure 8. (A) The effect of pQFYRFamide on the C2 neuron at -45 mV is accompanied by an increase in conductance as indicated by the increase in current pulses evoked by periodically stepping the voltage to -80 mV. (B) Relationship between peak current and holding poten- tial (Vh) for responses evoked in physiological solutions containing ei- ther the normal (5 , circles) or reduced ( , squares) level of potassium in an experiment on a single C2 Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Cl
Size: 1837px × 1360px
Photo credit: © Library Book Collection / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
