Practical pathology; a manual for students and practitioners . cipally, ofsmall round cells, and is traversed by a number of vessels. In themass of granulation tissue are small tubercle follicles, either single or ingroups, with their giant cells and typical structure. (See § 246.) Thistissue corresponds to the area of gelatinous tissue seen with the nakedeye. Where caseation is complete, the bone has entirely disappeared, TUBERCULOUS CARIES 593 or is represented by small detached fragments or spicules, betweenwhich are granular shrivelled cells, droplets of fat (stained black withosmic acid,
Practical pathology; a manual for students and practitioners . cipally, ofsmall round cells, and is traversed by a number of vessels. In themass of granulation tissue are small tubercle follicles, either single or ingroups, with their giant cells and typical structure. (See § 246.) Thistissue corresponds to the area of gelatinous tissue seen with the nakedeye. Where caseation is complete, the bone has entirely disappeared, TUBERCULOUS CARIES 593 or is represented by small detached fragments or spicules, betweenwhich are granular shrivelled cells, droplets of fat (stained black withosmic acid, § 135), in fact, simply a mass of caseous debris. ( X 300).—Confirm the above appearances. In the granulationtissue tubercle follicles are developed, after which the whole undergoescaseation, as is the tendency in all tubercle formations. Near the centreof the caseous mass the absorption of the trabecul^e is complete. There are also described in connection with bone three other formsof tuberculous lesion—(i) Miliary granulations found in general tuber-. FlG. 192.—Tuljcrculous necrosis of bone. A vertical transversesection of the upper end of the femur from a case of tuberculousarlliritis of llie hip, showing a wedge-sequestrum in the cervix,abutting by its base on the epiphyseal cartilage. (H. A. Thomson.) • a. Position of epiphyseal plate. b. Articular surface of head. c. Trochanter major. d. Sawn section. culosis. (2) The chronic circumscribed tuberculous focus of Konig,which varies in size from that of a pin-head to that of a cherry, has atranslucent periphery of a reddish-grey colour, and appears well definedto the naked eye (H. A. Thomson). These nodules have all thecharacteristic appearances of tubercle. They appear to be formed bya fusion of several smaller nodules, which bring about erosion of thebone, caseation takes place in them, and they break down in thecentre, just as do all other caseous tubercle nodules; extension takesplace at the periphery. (3) A thi
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