. A practical study of malaria. in theBaltimore Observer, 1807, no such article has been found,and the reference is probably erroneous. In 1848 Dr. Josiah Nott,2 of Mobile, published a paper uponyellow fever, in which he maintained the dissemination of thatdisease by insects, and suggested that malaria was spread bythe mosquito of the lowlands. The most complete theory was proposed by King3 in views are supported by nineteen arguments, most of whichare incontestable at the present day. That mosquitoes are agents in the spread of malaria wasadvanced by Koch in 1884, by Laveran in 1884,
. A practical study of malaria. in theBaltimore Observer, 1807, no such article has been found,and the reference is probably erroneous. In 1848 Dr. Josiah Nott,2 of Mobile, published a paper uponyellow fever, in which he maintained the dissemination of thatdisease by insects, and suggested that malaria was spread bythe mosquito of the lowlands. The most complete theory was proposed by King3 in views are supported by nineteen arguments, most of whichare incontestable at the present day. That mosquitoes are agents in the spread of malaria wasadvanced by Koch in 1884, by Laveran in 1884, by Fliigge in1891, by Manson in 1894, and by Bignami in 1896. Undertaking the work at Mansons suggestion, and afterseveral years (1895-1898) of toil and discouragement, Rossproved conclusively that certain species of mosquitoes are con-cerned in the dissemination of malaria. The debt owed himby mankind was acknowledged by the gift of a Nobel prize;his own feelings over the discovery are expressed in these lines,which he wrote:. Fig. 2.—Major Ronald Ross, the discoverer of the role of the mosquito. INTRODUCTION 23 This day relenting God Hath placed within my handA wondrous thing, and GodBe praised. At his command Seeking His secret deeds, With tears and toiling breath,I find thy cunning seeds,Oh million-murdering death. I know this little thing A myriad men will save;Oh, death, where is thy sting,Thy victory, oh grave? A discovery, secondary in importance only to those ofLaveran and of Ross, was made by MacCallum in 1898, whodemonstrated that the flagella represent male sexual elements,analogous to spermatozoa. HISTORY OF HEMOGLOBINURIC FEVER It is probably unique in historical pathology that a complexof symptoms so striking as hemoglobinuric fever should havesuch an obscure history. As this obscurity is intimately asso-ciated with the etiology and symptomatology of the conditionan investigation of some of the factors in its history is notwithout interest. After a short state
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Keywords: ., bookcentury1900, bookdecade1900, booksubjectmalaria, bookyear1909
