. The Biochemical journal, 1917. Biochemistry. 352 J. a DRUMMOND tyrosine, cystine and tryptophan are added to gelatin, and the deficiencies of the latter thereby to a large extent made good, nitrogen equilibrium can be established. His work has received confirmation from that of Rona and Miiller [1906] and Abderhalden [1912]. More recently the subject has been carefully in- vestigated by Totani [1916], who found that the addition of tryptophan to gelatin greatly raised its nutritive value. The effect of adding the missing tyrosine was hardly appreciable; so that the author was led to suggest
. The Biochemical journal, 1917. Biochemistry. 352 J. a DRUMMOND tyrosine, cystine and tryptophan are added to gelatin, and the deficiencies of the latter thereby to a large extent made good, nitrogen equilibrium can be established. His work has received confirmation from that of Rona and Miiller [1906] and Abderhalden [1912]. More recently the subject has been carefully in- vestigated by Totani [1916], who found that the addition of tryptophan to gelatin greatly raised its nutritive value. The effect of adding the missing tyrosine was hardly appreciable; so that the author was led to suggest that the animal organism may have the power of synthesising the benzene nucleus. Rat Days 12 19 26 33 40 lleniarks Weight of tumour Weight of rat — tumour 8- rhaiijfu in weight of rat . Cbaugt- ivi-iglrt per 1 g 6 9 9 cr 9 • • t 0 • • • • • • • • • • f t • - - Tiiinuui' slightly necrotic. Animal thin. dill.) (ill to Tnnionr Hi'in iiiid fihious. Animal thin. I'limour retrogressed 14 0 14 0 70 20 780 690 920 900 ^9 0 -12 0 -80 -10 0 Average 92 - -98 -106 12Q- 100- 40- 1- .^. CT Hat J- Tumour X--.^ Chart 13. Tumour development, and growth curves of normal and tumour-bearing rats upon Zein diet (Chart 12) + 0-5 % tryptophan. Tumour ;Sf/1166. The investigation of the influence of the amino-acid deficiencies of gelatin upon tumour growth, which are described in this paper, was carried out before the appearance of Totani's communication, so that his observation upon the more complete assimilation of gelatin administered in the hydrolysed. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Biochemical Society (Great Britain); University of Liverpool. Biochemical Dept. London [etc. ] Cambridge University Press
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