A system of surgery . previous trouble. 3. A diffused osteitis, terminating in osteosclerosis of nearlythe whole shaft of a Jong bone, may, however, be present withoutany definite node, as above described. When this is the case, manybones are affected, and generally in a symmetrical manner. Theyare as intractable as in the former instance, but relief of the severer GUMMATA OF BONE. 893 symptoms may be obtained by large doses of iodide of potassium,with or without the addition of mercury, according to the effectproduced by the former drug. 4. Gummata Of bone are nearly always associated with pe


A system of surgery . previous trouble. 3. A diffused osteitis, terminating in osteosclerosis of nearlythe whole shaft of a Jong bone, may, however, be present withoutany definite node, as above described. When this is the case, manybones are affected, and generally in a symmetrical manner. Theyare as intractable as in the former instance, but relief of the severer GUMMATA OF BONE. 893 symptoms may be obtained by large doses of iodide of potassium,with or without the addition of mercury, according to the effectproduced by the former drug. 4. Gummata Of bone are nearly always associated with peri-osteal nodes or a more or less diffused osteosclerosis. Some portion ofthe inflammatory infiltration, whether it be in the periosteum or in thebone, softens, and presents the ordinary characters of a gumma. (Seepage 408 and Fig. 82.) The overgrowth of connective tissue whichat one part organises and at another undergoes degenerative changesis the most characteristic feature of syphilis when it attacks the .Caries. Necrosis. Fig. 337.—A Portion of the Frontal Bone showing its outer Surface. An irregular sequestrumof which a large portion is carious, and involving both tables of the skull unequally, hasbeen completely detached from the surrounding sclerotic bone.(St. Thomass Hospital Museum, No. 559.) bones, as it is when other organs are affected. An enlargement ofbone, painful at night and tender on pressure, is the first indicationof this, as of other diseases of bone. The special feature of its gum-matous nature is the presence in some part of the swelling of a smallarea of fluctuation. If this remains untreated, the skin will event-ually give way, discharging a thin watery fluid, and leaving an aper-ture with an irregular, perhaps crescentic, margin, like the gummatousulceration of soft parts, leading to diseased bone. If the originalswelling has been a softening periosteal node, the portion of boneaffected will be the cortex only ; but if the whole thickness


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