A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . ls there is an increase in the connectivetissue and destruction of large numbers of capillaries,still further diminishing the size of the vascular bed,and then comes a disparity between the caliber of theartery and the territory to be supplied, followed by acompensating growth of connective tissue. Council-man would rather take the view that the changes inthe aorta and in the minute arteries are due tothe same cause; that diffuse endarteritis is a dis-ease primaril
A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . ls there is an increase in the connectivetissue and destruction of large numbers of capillaries,still further diminishing the size of the vascular bed,and then comes a disparity between the caliber of theartery and the territory to be supplied, followed by acompensating growth of connective tissue. Council-man would rather take the view that the changes inthe aorta and in the minute arteries are due tothe same cause; that diffuse endarteritis is a dis-ease primarily due to a degeneration of the muscularfibers of the media. On this the growth of the intimafollows, which is due to the same cause acting in two?ways: in one, by the well-known law of connective-tissue growth, to supply a defect, in this case the de-generation of the media; and in the other, possiblyacting under the law of Thoma, a compensatingendarteritis to restore the abnormally dilated vesselto a normal caliber. Nodular A rleriosclerosis.—In the nodular or primaryform of arteriosclerosis there are flat, button-like,. Fig. —Xodular Sclerosis nf .\orta with Beginning Aneurysm. Hematoxylin andWeigerts elastic-fiber stain. The intima (I) is thickened, contains parallel, wa\j-,elastic fibers, except at the point of the bulging: the media (M) is thinned, degen-erated, the elastic broken up: A, adventitia. X 150. hemispherical, yellowish or yellowish-white pro-jections above the intima, about the orificesof the arterial branches. This is generally regardedas the result of the greater strain that this part of theartery is exposed to. The areas consist of new con-nective and new elastic fibers in the intima,the underlying media being either fibrous, calcareous,or degenerated and necrotic. Thoma claimed thatthe cast after filling the ves.^el with melted paraffininjected under the same pressure as that of the bloodcame out smooth, showing that in the tense
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Keywords: ., bookauthorbuckalbe, bookcentury1900, bookdecade1910, bookyear1913
