. The breast: its anomalies, its diseases, and their treatment . cinoma-tous parenchyma and sarcomatous stroma occur in the same tumor, either throughsarcomatous transformation of the stroma of a carcinoma or through carcinomatoustransformation of the epithelium in a benign tumor, and (c) when in certain tumors—endotheliomas, etc.—substantially sarcomas, nests of cells occur in such manner as toappear like carcinoma—false carcinosarcoma. 4IO THE BREAST Tumors of double structure of the kind indicated are not infrequently called mixedtumors, and are thought by some pathologists to arise through


. The breast: its anomalies, its diseases, and their treatment . cinoma-tous parenchyma and sarcomatous stroma occur in the same tumor, either throughsarcomatous transformation of the stroma of a carcinoma or through carcinomatoustransformation of the epithelium in a benign tumor, and (c) when in certain tumors—endotheliomas, etc.—substantially sarcomas, nests of cells occur in such manner as toappear like carcinoma—false carcinosarcoma. 4IO THE BREAST Tumors of double structure of the kind indicated are not infrequently called mixedtumors, and are thought by some pathologists to arise through defective embryonaldevelopment. The discovery of their duplex nature is usually made by microscopic examination ofthe tumors; sometimes both tumors are clearly visible as separate entities. In most cases the tumor was clinically diagnosticated carcinoma; in a few cases itwas diagnosticated sarcoma. There can be no doubt but that the tumors arise in differentways. Thus in the case described by Coenen (Beitrage zur klinischen Chirurgie, tqio,LXVIII, 6c5).. Fig. 155.—The carcinomatous part of the breast reported by Kennedy and Case. The tumor which occurred in the right breast of a woman 43 years of age, was known to have existed/or 14 years. It finally attained to the size of two fists. When examined microscopically, the greaterpart of it was found to be largely composed of spindle cells without inter-cellular substance; some por-tions contained many giant cells, others were myxomatous. Scattered through it were nests of carcinomacells. The axiUary lymphatic nodes were enlarged, and when examined showed metastasis of carcinomaonly. Five months subsequently other metastatic formations showed sarcoma only. A tumor of 14 years duration, with spindle- and giant-cell structure ought to fallamong the sarcomas arising from benign fibro-epithelial structure. According to theviews that we entertain, both the sarcomatous change of the stroma and the carcinoma-tous change in the ep


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbreast, bookyear1917